While gout often affects the big toe, it can also develop in the finger joints and cause knuckle pain. Any injury in the fingers or the hand can lead to knuckle pain. A finger dislocation means that ...

Osteoarthritis most often affects the joints of the hands, knees ... rubbery bumps on the thumb and knuckles called rheumatoid nodules. People with gout may develop crystallized lumps in the ...