Aim To describe clinical features and outcome of a series of children with first-episode optic neuritis investigated in three paediatric neurology centres. Methods Databases were searched to identify ...

Introduction Optic neuritis (ON) results in acute loss of vision with pain on eye movement ... Interestingly, none of the patients developed significant symptoms in the contralateral eye with vision ...

Methods ACTION is a phase II randomised controlled trial of amiloride vs placebo in patients with acute optic neuritis, recruited within 28 days of onset ... Results 14 patients have been recruited ...