Lockard’s 1-year-old daughter Naomi had just been diagnosed with hereditary spastic paraplegia-50, or SPG50, a condition known to affect around 100 people on the planet.

We describe a family with pure X-linked hereditary spastic paraplegia (HSP) and report linkage to X-chromosome DNA probes. A 6-generation pedigree (K313) with 12 affected males is presented.

We had every gene in her body mapped, and at 14 months old, Tallulah was officially diagnosed with Hereditary Spastic Paraplegia Type 56 (SPG56) - an incurable brain disease so rare no one else in ...

Hereditary spastic paraplegia, or HSP, is a group of movement disorders that cause progressive weakness and stiffness in the ...

Our research can shed light on the connection between the endoplasmic reticulum and many diseases, such as Alzheimer's disease and Hereditary spastic paraplegia.

In particular we are investigating the involvement of axonal transport in diseases including motor neurone disease (MND) and hereditary spastic paraplegia (HSP). In addition we are developing and ...